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All About Keratinocyte Growth Factor (KFG)

Written By: The Serum Guru

A primary active in our RevivHair Stimulating Serum and RevivLash Lash & Brow Stimulating Serum: Keratinocyte Growth Factor (KGF or rh-Polypeptide-3). Numerous scientific/clinical studies show how KGF helps promote hair growth. Check out these published articles:

Danilenko, Dimitry M.; Ring, Brian D.; Yanagihara, Donna; Benson, William; Wiemann, Bernadette; Starnes, Charles O.; Pierce, Glenn F. (1995). Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia. American Journal of Pathology 147: 145-54.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1869891/pdf/amjpathol00043-0151.pdf

Richardson GD; Bazzi H; Fantauzzo KA; Waters JM; Crawford H; Hynd P; Christiano AM; Jahoda CA. (2009). KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.
http://www.ncbi.nlm.nih.gov/pubmed/19474150

Karvinen, S; Pasonen-Seppanen, S; Hyttinen, JM; Pienimaki, JP; Torronen, K; Jokela, TA; Tammi, MI; Tammi, R (2003) Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan syntheses 2 and 3. J Biol Chem, 278:49495-49504
http://www.ncbi.nlm.nih.gov/pubmed/14506240

Braun S; Krampert M; Bodó E; Kümin A; Born-Berclaz C; Paus R; Werner S. (2006) Keratinocyte growth factor protects epidermis and hair follicles from cell death induced by UV irradiation, chemotherapeutic or cytotoxic agents Journal Cell Science, 119: 4841-4849
http://www.ncbi.nlm.nih.gov/pubmed/17090603

Jang, JH (2005) Stimulation of human hair growth by the recombinant human keratinocyte growth factor-2 (KGF-2). Biotechnology Letters, 27:749-52.
http://www.ncbi.nlm.nih.gov/pubmed/16086254

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