RECHARGE THE SKIN
FOR LIFELONG YOUTHFULNESS
Representing the pinnacle of cosmetic chemistry, TelomErase Serum combines the latest anti-wrinkle technology and patented actives to stimulate the skin's power to rejuvenate. The first product of its kind with three proven telomere targeters: Cycloastragenol + Renovage® + Telosomyl®. The latest in cosmetic chemistry spotlighting telomere stabilization.
See the international press about its debut here
TelomErase Triple Telomere Targeting Serum is next-gen age-defying technology: a 6-in-1 multi-corrective that erases, tightens, brightens, blurs, moisturizes and regenerates. It contains the most powerful combination of new ingredients available to visibly reduce the appearance of sags & bags, dark circles, fine lines, sunspots, redness, pore size & laxity.
A conference by Nobel laureate Dr. Elizabeth Blackburn at the recent American Academy of Dermatology conclave in San Francisco underlined the clear correlation between telomere length and integrity with overall health and skin condition. Protecting telomeres is a valid strategy to maintain healthy skin, Dr. Blackburn noted. A study from Harvard Medical School showed that telomere shortening is a root cause of cellular aging. An enzyme, telomerase, has been shown to slow or even reverse telomere shortening that occurs as we age, but the amount of telomerase declines as we get older. The development of a sensitive and efficient telomerase activity detection method has only recently made it possible to quantitate telomerase activity. TelomErase Serum contains three proven ingredients shown to target telomerase.
In a 30-day, 22-person consumer study of TelomErase, over 90% of consumers tested noted a reduction in the appearance of skin laxity & skin roughness, 88% agreed that the area around the eye appeared improved; 74% of testers also saw a reduction in the appearance of redness and large pores, and 90% agreed that it made their skin more soft or smooth.
About The Key Ingredients:
CYCLOASTRAGENOL is a novel molecule isolated from the astragalus membranaceous root. This hard-to-source ingredient has been shown to have telomerase activation activity both in vivo and in vitro and has been shown to reverse visible signs of aging. It is the same key ingredient in new products like TA-65™ from TA Sciences ($500 for 1 oz.) and Regeneration Booster™ from Jan Marini® ($210 for 1 oz). more
TELOSOMYL® is a unique ingredient enriched in linear galactans derived from a particular type of red algae, Kappaphycus alvarezii. According to its developer, France-based Silab S.A., TELOSOMYL when tested on pre-senescent human fibroblasts, significantly reduces stress-induced telomere shortening by 65%. In another study, 75% of human test subjects received more than a 30% improvement in the appearance of the dermal matrix. In a fringe projection study, TELOSOMYL improved skin roughness in 79% of the test subjects, and improved skin volume in 67%. more
RENOVAGE™ has clinically proven anti-aging effects by addressing telomere stabilization. According to Sederma, its developer, patent-pending Renovage reduces telomere shortening in stressed and non-stressed replicating human skin cells, maintaining telomere length. It also reduces heat shock protein release in stressed cells.
Tested on human skin fibroblasts that had arrived at a pre-senescent state (where the cells no longer divide), the average length of telomeres shortens by 630 bases (building blocks) in the control group, and by only 200 bases in the group treated with Renovage. It's a key ingredient in the comparative product myHero™ Youth Serum ($225.00 for 1 oz).
In a blind study, 100% of human test participants experienced improvement in the appearance of UV sun spots, as well as 24-hour skin moisturization; 90% of panelists had an improvement in pore size; 75% had improvement in skin firmness. more
PEPHA®-TIGHT is a unique natural tightening and firming active ingredient that delivers both a fast, instant tightening experience, and a superior long term skin firming effect. PEPHA®-TIGHT is a highly purified biotechnologically produced extract from the microalgae Nannochloropsis oculata combined with a well-balanced fraction of polysaccharides. According to its developer, Swiss-based DSM, its instant perceivable tightening effect lasts for at least four hours after application, with long-term firming effects, stimulating the formation of collagen. more
EYESERYL®: A tetrapeptide with a recognized efficacy against puffy eyebags, Eyeseryl reduced eyebags in 70% of test volunteers after only 15 days, as well as decreased dark circles under the eyes by inhibiting vascular permeability. It can also provide a visible lifting action on sagging upper eyelids. more
REGU®-AGE: is specially purified soy and rice peptides and yeast-derived superoxide dismutase. It has been shown to visibly reduce dark circles and eye puffiness, strengthen connective tissue, reduce inflammation and prevent UV damage. In a 4-week treatment study, a reduction of eye puffiness of 25%, and reduction of dark circles by 32% was observed. more
aFGF (Recombinant Human acidic Fibroblast Growth Factor): This growth factor or cytokine helps stimulate skin stem cells to rejuvenate both the epidermal cells and the underlying fibroblast cells, which produce collagen, elastin, and hyaluronic acid. aFGF can help remove the appearance of pigmentation, improve complexion, reverse skin damage and tighten skin.
SYMSITIVE™ 1609: TelomErase Serum contains some potent ingredients that might otherwise be somewhat aggressive for the most sensitive skin. SymSitive works as a fast-acting “anti-nerve hyper-activator” to calm over-reaction of hypersensitive skin, and help prevent stinging, burning & tingling. According to Symrise, its manufacturer, SymSitive works at the cell communication level, directly connecting with a specific neuro-receptor — the TRPV1 thermo-receptor — bringing skin sensitivity back to a normal state to increase skin-tolerance and, over time, help to increase the skin’s resistance against stressors. more
NANO-LIPOBELLE™ DN CoQ10: A supersaturated CoQ10 double phospholipid nano-emulsion, Nano-Lipobelle DN CoQ10 contains ultra-small particles of highly purified coenzyme Q10, tocopherol (vitamin E) and ascorbyl tetraisopalmitate (vitamin C), creating a liposome. Together, they ensure fast penetration into deeper skin layers to maintain activity & potency and become a potent moisturizer. Coenzyme Q10 (ubiquinone) is an essential component of energy metabolism in cells, and is a superb antioxidant. Ascorbyl Tetraisopalmitate is a novel, potent (and expensive) form of Vitamin C ester. Like other forms of Vitamin C, it works as a powerful antioxidant and whitening agent, with anti-acne and anti-aging capabilities, and can help prevent cellular aging by inhibiting the cross-linking of collagen and lipid peroxidation. Unlike L-Ascorbic acid, Ascorbyl Tetraisopalmitate does not exfoliate or irritate the skin and is suitable for even the most sensitive skin types. more
ASTAXANTHIN: A keto-carotenoid regarded as one of the strongest antioxidants in nature. It is famous for its “super vitamin E” content and is 550 times more effective than vitamin E, thought to be through its suppression of NF-κB activation. In addition to the compound’s powerful anti-irritation and anti-oxidative capabilities, evidence indicates that astaxanthin has the potential to modulate aging. It targets free radicals and thus UV induced skin damage, wrinkles & hyperpigmentation.
ADDITIONAL KEY INGREDIENTS: Hyaluronic Acid, Hydrolyzed Collagen, Sea Kelp Bioferment, Bisabolol and Sodium PCA all contribute to healthier, vibrant skin and help alleviate the signs of aging.
Reference: Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 2011 Jan 6;469(7328):102-6. http://www.nature.com/nature/journal/v469/n7328/full/nature09603.html
Cycloastragenol extends T cell proliferation by increasing telomerase activity http://www.jimmunol.org/cgi/content/meeting_abstract/182/1_MeetingAbstracts/90.30
Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances: http://www.the-scientist.com/?articles.view/articleNo/42253/title/Rethinking-Telomeres/
Instructions For Use:
Apply a thin layer to clean, dry skin (face, neck, chest and hands) once or twice daily for two to three months, then three times weekly thereafter for maintenance. A slight initial tingling sensation upon application is normal. Suitable for the upper eyelid orbital bone area if tolerated, but avoid contact with eyes and mucous membranes. Decrease frequency or discontinue use if irritation develops. For external use only.
Note: Because of patent restrictions, not to be sold or shipped to Japan.
Full Ingredients (2 oz/60 ml):
Note from our legal eagles: Astonishing Developments Ltd. and its RevivSerums.com products, including its TelomErase product, are neither affiliated with, nor approved by, Jan Marini Skin Research, Inc., nor T.A. Sciences Inc., nor mybody, LLC. Other company and/or product names may be trade names, trademarks and/or registered trademarks of the respective owners with which they are associated. None of our products are intended for use in the cure, mitigation, treatment or prevention of disease and/or are not intended to affect the structure or any function of the human body. Any testimonials on this website are based on individual results, and do not constitute a guarantee that you will achieve the same results.