Reference data for RevivHair Stimulating Serum and its primary ingredient, Redensyl

Trichogram photographs (from the double blind versus placebo clinical trial, grade 3 to 4 alopecia volunteers) display the results after only three months. The subject on the far-left (52 year old tester) had 28,200 new hairs (+ 47 hairs per cm2). Of course, at three months they are not "full-length" hairs, but obviously enough to show a visible, discernible difference, and as you can see the growth is evident on both the hairline and crown. A reminder that the average person has at least 100,000 or more hairs on the scalp, so it makes sense that this tester visibly shows a 28% increase in density in the photograph.

The 28,000 number is a maximum experienced by the testers in the study; the average was less. Perhaps the most striking effect was that hair fall decreased 17%, and we have many customers who have commented (and posted reviews) that they experienced real results within just a week or two of starting RevivHair Stimulating Serum, primarily by it noticeably/abruptly stopping existing shedding. While everyone is of course "bio-individual" you may very well find that you can expect this effect in just a few weeks of use.
The efficiency of Redensyl® at 3% was evaluated in the double-blind test versus a placebo. Twenty six male volunteers were selected by following specific inclusion criteria: between 18 to 70 years old, brown to dark hair, with a minimum density of hair of 150 hair/cm2 and 40 telogen hair/cm2, with clinically confirmed grade 3 to 4 alopecia. Volunteers applied the placebo or the product with 3% of Redensyl® on their whole scalp daily for 3 months.

A shaved area of 1.5cm2 was defined on each volunteer to allow the measurements on a window of 0.7cm2 at D0, D28 and D84. Phototrichograms were realized using a NIKON camera associated with Canfield® Epiflash System and a contact plate to press hair on the scalp. Analysis were run with Photoshop CS5 extended® and permitted to define if hair were in anagen, telogen or undetermined phase.

Results: A non significant placebo effect is observed (mechanical activation of micro-circulation), with almost no more evolution after 1 month. Redensyl® increases the percentage of hair in anagen phase by 9% compared to T0 after 3 months, and decreases the percentage of hair in the telogen phase by 17% compared to T0 after 3 months.

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Global news of our new RevivHair Stimulating Serum formulation with Redensyl

 

Reviv Serums is one of the first companies in the world to formulate a product with Redensyl® from Induchem, and this long-awaited product launch news has been picked up by almost 1000 different syndicated networks and online sites! It's been featured on the giant Reuters News sign in Times Square four different times already, and hit the wires on Reuters, DOW Marketplace, Yahoo, The Boston Globe, among many others. Here's just a sample list of the many, many articles:

 

 cbs8hd.com  wdam.com  kttu.com  wfsb.com  wxvt.com  tulsacw.com  weht.com  ksby.com  nebraska.tv  km3news.com 

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RevivSerums.com Launches First Swiss Hair Stimulating Redensyl Product in U.S.


FOR IMMEDIATE RELEASE
Contact: Bill Henderson
Email: pressrelations@revivserums.com
Phone: (415) 763-7248

RevivSerums.com Launches First Swiss Hair Stimulating Redensyl Product in U.S.

SAN FRANCISCO, JULY 31, 2014 /PRNewswire/ – RevivSerums.com is the first North American company to bring a hair care product to market containing award-winning Redensyl® from Swiss-based Induchem®.

Designed for both men and women, this novel next-generation leave-in serum can help significantly boost hair density, thickness, fullness, natural color, strength, and overall health.

"We are delighted to be one of the first to bring Redensyl to market, and to augment our popular and effective hair stimulating serum with this unique active," said Astonishing Developments' Director of Lotions and Potions Vance Nesbitt and principal formulator. "In updating one of our most popular products, we make it even more potent and effective while still maintaining its current price point of $49 (a $100 value). And with the addition of new polymers, it is even better for daily use since it instantly strengthens and thickens existing hair without making the hair stiff, oily, or smelly."

Induchem, creator of Redensyl, is a leading Swiss producer of specialty cosmetic actives for the personal care and cosmetic industry, with a worldwide presence including U.S.-based Induchem USA, Inc. in New York City. 

"As we further build our premier global brand in clinically proven personal care ingredients, we are excited about the continued growth potential in the U.S. market for us and for RevivSerums,” said Induchem U.S.A.'s General Manager Parand Salmassinia. "We're looking forward to a very productive working relationship that will benefit customers across the nation.”

Award-Winning 

Redensyl won In-Cosmetics 2014 Silver Award for Best Ingredient at its annual global showcase for personal care ingredients in Hamburg this past spring (http://www.induchem.com/news-home/redensyl-silver-award-at-in-cosmetics-2014/). 

Induchem cites Redensyl to be "the first cosmetic alternative to hair transplantation surgery." The product combines two patented Induchem molecules - DHQG and EGCG2 - to reactivate hair growth by targeting hair follicle stems cells, reactivating the proliferation of ORSc stem cells, protecting them from apoptosis, maintaining their differentiation properties, and activating the metabolism of dermal papillary fibroblasts.

Induchem's clinical assessment on volunteers produced outstanding results for Redensyl. In less than three months, 85 percent of the volunteers had significant and visible hair growth, with +9 percent of new growing hair and -17 percent of falling hair, enabling up to +28,200 new hairs in 84 days.

Redensyl yields almost two times the score of the worldwide reference minoxidil, according to Induchem.

Effective Ingredients 

RevivSerums is now incorporating this innovative, award-winning product in a new formulation of its popular 5 star-reviewed RevivHair Stimulating Serum.

In addition to the incorporation of Redensyl, RevivSerums is updating its hair stimulating serum with several additional new breakthrough ingredients:

• PhytoCellTec™ Argan, from Swiss-based Mibelle AG Biochemistry, is the first cosmetic active with proven efficacy on dermal stem cells. Hair follicles represent a highly relevant and efficient penetration pathway and reservoir for topically applied substances. Dermal papilla, where the dermal stem cell pool is localized, can be reached over follicular penetration. Sox2 expression is enhanced and “stemness” of the dermal stem cells is improved which in turn induces the repair of hair follicles.

• Cellulosomes® Crithmum Maritimum ST from Seppic® is an exclusive Sea Fennel stem cell culture that helps promote better epidermal metabolism, increases cell renewal, and the synthesis of collagen, proteoglycans, and glycosaminoglycans.

In addition to these breakthrough new ingredients, RevivHair Stimulating Serum contains its armament of remarkably effective, novel actives:

• Human Keratinocyte Growth Factor (KGF, rh-Polypeptide-3); PhytoCellTec™ Malus stem cells; Prezatide Copper Acetate; Myristoyl Pentapeptide-17; Copper Tripeptide-1; Acetyl Tetrapeptide-3; Biotinoyl Tripeptide-1; Palmitoyl Tripeptide among other superb actives.

The revised formula is now fragrance-free, and its base is a light, almost clear, formulation safe for all hair colors and hair types.

In addition to these innovative new ingredients, Reviv Serums is now providing PDPO (Pyrrolidinyl Diaminopyrimidine Oxide -- trade name Triaminodil™) in a separate optional vial for customers who want the growth-regulating effects similar to its chemical cousin minoxidil, which is a Pyrimidinediamine Piperidinyl Oxide. The vial ingredient is optional for those users who don't mind potential initial increased shedding since this ingredient can help promote the transition from the telogen (resting) phase to the anagen (growing) phase of the hair cycle. The vial is a customer add-on, and is only $5.

Revivair Stimulating Serum is meant to be used once or twice daily in addition to regular styling products or products such as minoxidil, and is applied directly to the scalp. 

Note: The serum is considered a cosmetic, not a drug, and the product is not intended for use in the cure, mitigation, treatment, or prevention of disease and/or is not intended to affect the structure or any function of the human body.

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Quick Links

Social Media
#RevivSerums  #Redensyl  #Induchem  #hairloss  #hairgrowth

Product Packaging Photos
600 x 600 px (with "Indiglo" filter):  http://bit.ly/1mJqQ7r
4000 x 3000 px:  http://bit.ly/1nlamaF
1200 x 1200 px:  http://bit.ly/1jXGTDI

Graphics
RevivSerums logo file (black background): http://bit.ly/1l8RCqo
RevivSerums logo file (white background):  http://bit.ly/1x7nvou
Redensyl Silver Award Seal from in-Cosmetics:  http://bit.ly/1rDWKdi

Brochures
Redensyl Brochure:   http://bit.ly/1ke5YLe
PhytoCellTec Argan:  http://bit.ly/1rPeMXx
PhytoCellTec Malus:  http://bit.ly/1tGoITM
Cellulosomes Crithmum Maritimum ST:  http://bit.ly/1nXYjLH

Videos
PhytoCellTec™ Argan stem cells: https://www.youtube.com/watch?v=piwFnNY432U
PhytoCellTec™ Malus stem cells: https://www.youtube.com/watch?v=CnrQ7owWapQ

Company Websites
About RevivSerums.com
RevivSerums.com is a wholly owned component of Astonishing Developments Ltd., based in San Francisco, California. The company specializes in novel and innovative clinical treatment serums for skin and hair rejuvenation. They currently distribute throughout North America (U.S., Canada, Mexico), Europe and South Africa and are poised to enter markets in Japan.

Legal
RevivSerums is a trademark of Astonishing Developments Ltd. Redensyl is a registered trademark of Induchem Holding AG Corporation, Switzerland. Other company and/or product names may be trade names, trademarks and/or registered trademarks of the respective owners with which they are associated.

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Addressing greying hair isn't just a vanity issue; it's a scalp and skin health issue too.

Asian man examining premature greying hair

Addressing greying hair isn't just a vanity issue; it's a scalp and skin health issue too.

Premature greying of the hair is a condition known as canities; the diminishing of pigment in hair producing a range of colors from normal to white that is perceived as gray.

It is a complex multi-factorial process mainly considered to be an interplay of nutritional, genetic and environmental factors. Nutritional deficiencies like vitamin B12 deficiency, severe iron deficiency, chronic protein loss, copper deficiency are often found associated with premature greying of hairs. Other factors that have been incriminated are low serum ferritin, and low serum calcium and vitamin D3 levels.

Smoking is another factor that is considered to be related to premature greying of hair. Smoking results in generation of huge amount of reactive oxygen species leading to increased oxidative stress culminating into damage to melanin producing cells, melanocytes. Prolonged exposure to ultraviolet rays is considered to initiate similar processes in hair follicles resulting in premature greying of hair.

It turns out that a key factor in hair color loss happens to be the buildup of hydrogen peroxide in the scalp and hair follicles. As we age, our bodies become less able to neutralize that hydrogen peroxide, which interferes with an enzyme that is responsible for producing the pigment in hair. The graying begins when the synthesis of melanin (the natural pigment that gives hair its color) is disrupted.

https://www.ncbi.nlm.nih.gov/pubmed/24695442
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929555/

Another recent study in Nature Medicine suggests that sun damage may very well speed up the graying of hair. The study found that when UV exposure damaged skin, melanin-producing stem cells migrated upward to the skin to produce protective pigment (a tan) but abandoned their position in the hair follicle.

While there are many other factors that can contribute to graying hair (genetics, ethnicity, stress etc.), these studies suggest there are steps you can take to slow down or minimize graying hair:

The revolutionary ingredients, like Greyverse and Darkenyl, found in our RevivHair REV Stimulating Serum may help prevent hydrogen peroxide buildup and target tyrosinase to help prevent the loss of hair color and the appearance of darker hair, naturally without dyes or pigments. Another included ingredients (also mentioned in the study) may help: Methionine Sulfoxide Reductase.

Additionally, wearing a hat or applying a UV protection product for the hair (more specifically, the scalp) whenever you're outside, may help as well. Wearing a hat to shield UV damage is something we should be doing anyway!

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