Head To Head Comparison: Ultimate Serum™ vs. SkinMedica® TNS Essential Serum®

Ultimate Serum "Compare To" product to TNS Essential Serum from SkinMedica | Larger, Cheaper, 23 same ingredients

Ultimate Serum
is the first direct competitor to award-winning TNS Essential Serum® (NEWBEAUTY™ Beauty Choice Award Winner and InStyle™ Beauty Award Winner) by SkinMedica® which is now owned by Allergan, Inc. The patent on the TNS product relates to the medium called NouriCel-MD®, a "proprietary blend" of growth factors. We at Reviv Serums outflank this patent by simply providing our growth factors in a different conditioned media. In addition to the growth factors, we also include 42 of the top primary ingredients in TNS Essential Serum, and leapfrog by adding two of cosmetic chemistry's latest ingredients: stem cells and hexapeptides.

Regarding the percentage of growth factors in each product: In actuality, the growth factors in both products are quantities measured in micrograms. TNS just lists "conditioned media" as the first ingredient, and does not break down the quantities of the actual factors like EGF, KGF, VEGF, IGF, TGF, etc. Growth factors are signaling molecules, therefore very little volume/quantity is required to be active and effective (they are measured in micrograms, one millionth of a gram). Like a spark plug, a little bit will go a very long way, and more that the recommended quantity is not "better." As for the other non growth factor primary ingredients, they're the same - plus we add the PhytoCellTec® Stem Cells, hexapeptides, SYN-TC peptides, and microbiome probiotic technology. Ultimate Serum is 70% larger than TNS (50 mL / 1.69 FL OZ vs. 1.0 OZ) and yet is less than half TNS's hefty price of $281.00.

Ultimate Serum contains a safe Ecocert preservative — Optiphen Plus.

Ultimate Serum is really 11 different products in one:


• A brightening product
• An antioxidant serum
• A firming and tightening product
• An anti-inflammatory
• A peptide serum
• A green tea complex product
• A vitamin C serum
• A sebum controller
• A collagen stimulator serum
• A growth factor serum
• A moisturizer and light emollient


It’s the ultimate rejuvenator in a single serum. Navigate to its product page here.

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What IS a "serum"?!

Good question. While there are no hard-and-fast definitions, in general a serum is chemically different than a cream, lotion, balm or oil type of "emulsion" (a mixture of non-mixable components). Primarily, the difference involves the use -- or lack thereof -- of an emulsifier. Creams and lotions generally contain lipophilic (fat-loving/fat-soluble) ingredients which need an emulsifier to blend with hydrophilic (water-loving/water-soluble) ingredients. Often, ten times the amount of emulsifier is needed to go along with a fat-soluble ingredient, just to get it to blend.

By comparison, a serum doesn't contain many emulsifiers, or sometimes none at all. This leaves room for more potent, active ingredient percentages, so serums are almost always more powerful and concentrated than other types of emulsions. Typically, the active ingredients in a serum have a smaller molecular size than a lotion or cream so penetrate the skin faster, and deeper. Because the percentage of active ingredients is usually much more than in a cream, serums usually cost more, but of course can be much more effective.

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