SerumScoop: Tips, tricks and news
Sytenol® A Clinically Proven to Mitigate Multiple Signs of Acne
Percent reduction in acne was determined by Global Acne Grading System (Burke et al., British J Dermatol, 111:83-92, 1984). This system takes into account both non-inflammatory and inflammatory lesions. Based on the results, formulations containing 1% Sytenol® A reduced acne score by about 57% (Chaudhuri & Marchio, Cosm & Toil, 126:502-510, 2011).
Subjects – 15 x 4 with mild (up to 10 comedones) & moderate (10 to 25)
Duration of the study – 6 weeks
Frequency of application – Twice a day
Assessment of Efficacy –
o Acne score at initial day
o Reduction in comedones after 2, 4 & 6 weeks of treatment
o Reduction in erythema and pruritus after 2, 4 & 6-weeks of treatment
Results – Sytenol® A alone or in combination with Salicylic acid provide statistically significant improvement in acne-affected skin and is well tolerated.
Get the remarkable benefits of retinol-like Sytenol A in Revivinol "Unretinol" Serum. All of the benefits of a retinol -- none of the downsides!
Beauty Influencer @bawbby_ reviews new Revivinol Serum, the first dual powerhouse natural alternative to retinol — without the downsides!
“I just finished my 10th use of Revivinol Serum and I couldn’t wait to finally share my thoughts! My main area of concern was this horrible breakout of red bumps I’ve had on my forehead for TWO YEARS. Nothing I tried would fix it, so I covered it with makeup and airbrushing for photos. But after 10 days with this serum, the bumps are GONE and my skin tone has even improved! My entire face looks and feels the best it has in years. I am completely blown away, I thought nothing would ever work for my stubborn skin! I am being 100% honest when I tell you this serum has changed my life. I feel 110% more confident without those unsightly bumps and my red patches.
…this serum is truly amazing and I will continue faithfully using it and recommending it to EVERYONE. Nothing in my life has ever worked as well on my problematic skin as this serum!”
Get Revivinol Serum, a full 2 ounces in size, at a great price here at RevivSerums.com
Sytenol® A - A Functional Analog of Retinol From the perspective of topically applied compositions, a small molecule without having the negatives of Retinol that safely mimics the properties of Retinol (Fisher et al., FASEB J,1002-1013, 1996) is a greatly sought after ingredient.
Volcanic plots illustrate the molecular signatures of Retinol and Sytenol® A of a DNA microarray experiment using reconstructed full thickness epidermis. This shows a very similar overall shape, indicating similar overall modulation of gene expressions in the skin substitute model. Multiple comparative studies revealed Sytenol® A to be the true alternative to Retinol (Chaudhuri, In Cosmeceuticals and Active Cosmetics, 3r Edition, Eds., Maibach et al., Chapter 1, 1-18, 2015) for anti-aging applications and does not have the inherent safety & stability issues of Retinol.
A recent randomized, double-blind clinical study between Sytenol® A and Retinol carried out by UC-Davis Dermatologists demonstrated that both compounds significantly decreased wrinkle surface area and hyperpigmentation, with no statistical difference between the compounds. The Retinol users reported more facial skin scaling, burning and stinging. Authors concluded that Sytenol® A is a more tolerable alternative to Retinol (Dhaliwal et al, British J Dermatology, 2018 Jun 27. doi: 10.1111/bjd.16918).
Clinically Proven to Reduce Multiple Signs of Aging
• Human volunteers – 17; 16 Completed; Age – 41 to 60 yrs; Caucasian (14), Hispanics (2)
• Study duration – 12 weeks
• Test sites – Full face
• Test substance – Lotion with 0.5% Sytenol® A; Contains No sunscreen and No moisturizer
• Application frequency – About 2 g twice a day
• Methodology – Expert grading/Self-assessment by panelists (Grading 0 to 4): (1) Roughness & Dryness; (2) Fine lines & wrinkles; (3) Skin tone; (4) Skin elasticity & firmness; (5) Radiance; (6) Brightening; (7) Overall eye-area appearance; Silicone Replica Analysis: Wrinkle depth & Skin roughness; Photography: Before & after the treatments; Readings were taken at baseline, 4, 8 & 12 weeks.
• Statistical Analysis – Statistical significance defined as p ≤0.05
The results clearly showed that, after twelve weeks treatment, significant improvement in lines and wrinkles, pigmentation, elasticity, firmness and overall photo-damage was observed, with no irritating effect on skin. Based on these results and the comparative studies of Retinol and Sytenol® A done by Sytheon, we conclude that Sytenol® A is the first true Retinol-like anti-aging product (Chaudhuri & Bojanowski, Intern J Cosmet Sci, 36(3):221-230, 2014).
Get the remarkable benefits of Sytenol A in Revivinol "Unretinol" Serum here.
Stress is a part of life, and stress can affect the health and appearance of skin.
When the body is under stress, it releases cortisol, a regulatory substance transported in tissue fluids to stimulate specific cells or tissues into action.
This effect, over time, can negatively affect the skin in a number of ways.
While managing stress is of utmost important, it’s good to know there is topical help:
HA7X Multi-Molecular Hydrator Serum with Neurophroline™
Neurophroline is the first cosmetic active ingredient shown to address the visible effects of cortisol. It is derived from the wild indigo plant, Tephrosia purpurea, a native Indian plant used in Ayurvedic medicine for its skin benefits. Neurophroline also helps promote the release of endorphins which are relaxing neuropeptides in skin.
Neurophroline is the primary “hero” ingredient in HA7X Serum, which is the first U.S. product to contain this gold-award winning active.
Givaudan Active Beauty, the inventor of Neurophroline, has this to say about this remarkable ingredient:
Neurophroline™: think yourself younger
The revolutionary stress-busting active Neurophroline™, developed by Givaudan can not only combat the signs of environmental aggressors such as pollution and climate, but can also treat the real culprit of ageing – stress. Stress takes its toll on our skin, accelerating ‘wear and tear’ such as circles under the eyes, a fatigued appearance or fine lines. This breakthrough development from Givaudan triggers different actions in our physiological makeup to combat our stress hormones.
Romain, Givaudan’s R&D Director explains how it works: “Being stressed is actually bad for your skin; there are many products for anti-ageing, but none that target stress, despite the fact that this is a key ageing culprit.
“Our new product, Neurophroline™, stimulating the ‘feel good’ beta-endorphins and combating the main stress-hormone, cortisol.”
He continues: “We can tell whether the product is working by checking that the genes promoting the anti-oxidation are being stimulated. Anti-oxidation is a process that counteracts the negative effect of stress; this is scientifically important because of the link between feeling stressed and ageing skin. This powerful active ingredient generates results in two weeks, especially on high stress areas where the skin is thinnest, e.g. around the eyes."
Romain also gives insights into how feeling less stressed can make us look younger, and why: “Our skin and our brains share the same embryonic origin, meaning that how we feel inside affects how we look outside. If we are stressed, we will look tired, and age faster. If the brain thinks we’re happy and balanced, the skin will react positively… essentially we can think ourselves young again!”
Reverse the visible effects of stress on your skin. Get HA7X here today.
You can also get the remarkable benefits of Neurophroline for your LIPS with RevivLip Lip Renewal Serum System here!
Read more here:
Hair Strengthening Protein
Healthy hair is resistant to breakage because it demonstrates flexibility within its cortex as well as maintaining cuticle integrity. Through daily grooming and styling, hair is subjected to tensile forces, bending stresses and cuticle abrasion that ultimately cause a weakening of the hair fiber itself in addition to damaging the cuticle layer.
Increasing the strength of the hair is a two-fold strategy that must address both its inner flexibility along with the integrity of its surface layer. With an intermediate-range molecular weight of 1800, Keravis™ (INCI: Hydrolyzed Vegetable Protein PG-Propyl Silanetriol) addresses both of these issues by simultaneously penetrating the hair shaft to optimize moisture content and plasticity of the hair, while also forming a cross-linking film that coats the hair to lubricate, protect and reinforce the cuticle. Hair treated with the Keravis strengthening active shows a proven increase in hair strength - triple the strength of damaged hair compared to a control conditioner. Treated hair can demonstrate the increased resilience, flexibility and reduced breakage seen in healthy hair.
RevivHair Stimulating Conditioner utilizes this patented protein to address the three fundamental parameters of hair strength: tensile properties, bending modulus and cuticle abrasion.
See more on its product page here.
— Portions excerpted from Keravis datasheet and Cosmetics & Toiletries Magazine